Sentence examples for substantial selective pressure from inspiring English sources

Because the phenotype has likely been subject to a substantial selective pressure, the set of rare alleles is likely to include more genes of high penetrance, and fewer neutral genes, compared to more frequent alleles, all else being equally likely.

However, for this suggestion to be plausible, use of oseltamivir would have to be widespread to exert substantial selective pressure on the viruses.

It thus seems that female tissues/gametes maintain substantial selective pressure on codon usage even for genes with reduced expression, in a manner not characteristic of male tissues/gametes.

Its 16S rRNA genes are identical to those in the well-studied PCA strain, but the quantity of nucleotide polymorphisms and their strong enrichment at silent sites, as well as the diversity and distribution of genes that lack orthologs between the genomes all suggest the strains have been subject to substantial selective pressure since their divergence.

Our findings suggest that the E. coli core genome has been subjected to substantial selective pressures over time compared to the genome as a whole.

Examination of further Campylobacter phages has revealed positive matches between a number of them and the two genomes sequenced in this paper, with the implication that the two sequenced phages are well adapted to their particular niche and that there are substantial selective pressures on these phages to maintain this particular genome configuration.

Antibiotic is well recognized to impose strong selective pressure.

The number of CGVs increased despite the strong selective pressure.

The fact that in our model recombination has only a weak effect on virus load, however, is compatible with strong selective pressures on escape mutants, as observed experimentally [23], [43] [47], because large changes in viral fitness in vivo do not necessarily induce substantial changes in virus load [48], [49].

Viruses exert strong selective pressures on the defense system.

To reconstruct the evolutionary history of such sequences, one needs evolutionary models that take into account a substantial constant selective pressure.