Sentence examples for substantial selection in from inspiring English sources

If any other traits were under substantial selection in primordial genomes, and these traits were not perfectly congruent with error minimization, then an evolutionary process favoring increased fitness would yield a sub-optimal genetic code.

Since resistance has most commonly occurred in most patients undergoing long-term linezolid therapy [ 2], and the heavy use of linezolid in the patients may create substantial selection pressure in favor of linezolid-resistant isolate [ 5].

However, it has long been known that synonymous codon usage in bacteria is often strongly biased and is subject to substantial selection, especially in E. coli (Sharp and Li 1987; Ochman 2003; Sharp et al. 2005; Hershberg and Petrov 2008).

We estimate that fewer than 5% of all patients attending this Rheumatology clinic cannot speak English sufficiently to communicate with staff, so that in our view this inclusion criterion did not lead to substantial selection bias in the study and did lead to a representative sample of all clinic patients.

We found no evidence for substantial selection bias in a sensitivity analysis with conservatively imputed values.

However, in the ICU, a statistically significant increase in the use of linezolid was observed in 2004 and in 2007 (0.58 vs. 1.34 defined daily doses/100 patient-days, respectively); heavy use of linezolid may have created substantial selection pressure in favor of the linezolid-resistant isolates.

There is a lack of evidence for substantial selection bias in the AHS; the responses on the enrollment questionnaire of farmers who completed and returned the take-home questionnaire were remarkably similar to the responses on the enrollment questionnaire of farmers who did not return the take-home questionnaire (Tarone et al. 1997).

The lack of randomized, controlled studies may result in substantial selection bias.

A substantial selection of this material is in the show "William Blake's World: 'A New Heaven Is Begun' " at the Morgan Library & Museum.

In this regime, selection flips trigger adaptive substitutions, which occur at a rate γ L for independently evolving sites under substantial selection (Nf ≫ 1).

Despite substantial purifying selection in Verminephrobacter, we found clear evidence for relaxed purifying selection in the Vei and Vtu genomes relative to Acidovorax.