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Current studies provide strong evidence that neurodegeneration at substantial scale is the mechanism by which ethanol disrupts brain development in the rodent and, similarly, ethanol exposure disrupts development of the human fetal brain.
I would therefore enthusiastically support the sort of enterprise where a hospital ship equipped to do plasmaphoresis on a substantial scale is anchored off the coast of one of the affected countries and where convalescent donors are paid for allowing their blood to be taken and are transported by air to these ships where they are plasmaphoresed.
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The fact that they are there, that they are beginning to create their own music on a substantial scale, and are doing so on their own, without (so far) being dictated to or created by the big record companies, is very encouraging news.
Substantial economies of scale are gained when omics ancillary studies/variables are added to an existing cohort study.
The costs of addressing water quality issues on a global scale are substantial.
ODI = Oswestry disability index BDI = Beck depression index VAS = Visual analogue pain scale Both the intra and inter-rater repeatability of the retrospective 3-point surgical outcome scale was substantial (κ = 0.682, P < 0.001 and κ = 0.630, P < 0.001, respectively).
The correlation coefficient (t0 status and then-test) for the somatisation score was similar to the level of reliabilities of the scales; the correlation coefficients for the sleep scale and the physical functioning scale were also substantial.
For the CPQ11 14 group, the ICC for the overall scale was 0.92, indicating substantial agreement.
If true on a substantial scale, that would be an unhappy aspect of the crisis, since the most dangerous aspect of the Taliban insurgency within Pakistan itself these days is its spread into the mainland province of Punjab.
At present, resequencing on a substantial scale needs to be targeted to a specific locus [26].
The preferences that the admissions office is giving, Mr. Sander argues, are "on a substantial scale".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com