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This study provides evidence that direct transcervical passage is not a substantial route of direct embryo fetal exposure for small molecule drugs in semen.
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Across all five studies, there was substantial variation in drug dosage, route of administration of metformin, patient BMI, and patient levels of insulin metabolism before metformin treatment.
Prior studies have shown that inhalation exposure to semivolatile pesticides in indoor air can be substantial and may be a primary route of exposure after residential use among homes using insecticides (Fenske et al. 1990; Whitmore et al. 1994; Whyatt et al. 2002, 2003).
Adopting a visual analytic and modelling approach using a suite of regression models we find evidence to suggest that stickiness varies across the metropolitan area and over a 24-h period wherein higher stickiness is associated with high frequency users where there is substantial variability of route travel times across all alternatives.
The substantial influence of route has been documented in various monitoring and modeling studies (Adams et al. 2001; Hertel et al. 2008; Kingham et al. 1998; Strak et al. 2010).
Substantial evidence has indicated that direct human-dog contact might be a route of human infection based on the retained infectivity and pathogenicity of embryonated T. canis eggs recovered from dog hair [ 33- 35].
A substantial number of women had heard about malaria, but there was a knowledge gap regarding the route of malaria transmission.
13 The main route of HCV infection is injection drug use (IDU), and IDU is likely to explain a substantial proportion of the increased mortality in HCV infected patients.
Since inhalation is the most important route of exposure for NMs, these findings corroborate the assumption that the tested NMs do not elicit substantial adverse effects upon the experimental conditions applied in the present study.
Route of exposure.
We watch from the route of effluent.
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