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Because the clinical, regulatory, and economic impact of active control noninferiority trials is substantial, robust criteria should be used routinely in their design, analysis, and interpretation to reach their intended objectives and to keep them from becoming wasted efforts.
The range of concentrations at which VER-150548 enhanced gemcitabine and camptothecin cytotoxicity was substantial: robust potentiation was observed between 50 and 400 nM VER-150548 and correlated closely with increased DNA damage.
Janie [ 11] also appraised the development and delivery of effective partnerships for children (including reviews of them) and was unable to report substantial robust evidence of definitive impacts.
A complete resubmission with substantial, robust, and (reasonably rapidly doable) additional experiments could make for an acceptable new submission, which will be examined to see if it retains novelty and whether the hypotheses stand up after examination of results from the experiments suggested.
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A strong, robust, and legally binding Arms Trade Treaty must have the capacity to prevent transfers where there is substantial risk of violations of international humanitarian law or international human rights law.
The delay effect is substantial and robust.
These errors are smaller than estimates from similar corrections [25], but they are still substantial and robust across beverages.
Chakrabarti ([2001]) evidences that among the potential indicators of FDI, the role of market size/per capita GDP of a host country is the most substantial and robust.
Second, and related to the previous point, although Hume does not provide any substantial or robust theory of moral capacity, it is possible to find, within what he provides, material that suggests a less "rationalistic" understanding of moral capacity.
The effect is substantial and robust, holding across different measures of cognition and after adjustment for significant correlates of both CI and PI.
The tendency for abundant proteins to evolve more slowly was both substantial and robust, with all coverage sets showing significant correlations (Kendall's τ ranged from -0.31 to -0.49, P < 10-3) regardless of whether abundance was measured by expression level or CAI.
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