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First, it needs to be clear that environmental and social indicators that can be tracked and reported against will be legal conditions for approving high and substantial risk cases.
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"The violation in this case — the substantial risk of arbitrary and discriminatory vote-restoration based on an applicant's identity and perceived voting preferences from partisan government officials — is worse than a coin flip," Walker wrote.
Unsurprisingly, the newspapers believe their publications would not have created a substantial risk of serious prejudice to the case.
He said: "Having regard to the structure and terms of the takeover deal I am satisfied that there is a real and substantial risk of insolvency if the tax case were to be decided against the defenders (Rangers) in favour of the Revenue in the sums being spoken about".
The proposal hints at the inadequacy of borrower systems for high risk cases; this is true for substantial risk ones too.
Monitoring of atazanavir drug concentrations has mainly been recommended in special cases when there is a substantial risk of drug drug and/or food drug interactions (1).
A recent study of multiple-case breast cancer families in Australia suggested that two ATM variants, ATM 7271T→G and IVS10-6T→G, confer a substantial risk for breast cancer in families with multiple cases [ 19].
Mutation discovery was necessary in controls as well as cases, in order to distinguish a substantial risk attributable to rare alleles collectively from a high frequency of neutral mutations.
The proposed legislative and regulatory changes would allow abortion only in cases where there is a real and substantial risk to a woman's life — as distinct from her health.
In 1992, the Irish Supreme Court ruled that abortion was permissible in cases where there was a "real and substantial risk" to the life of a pregnant woman — including the possibility of suicide.
Restriction of our analyses to microscopically verified cases only would, in our opinion, have introduced a substantial risk of bias.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com