Sentence examples for substantial retardation from inspiring English sources

The liquid time and paste time increased dramatically, and we observed a substantial retardation of the polymerization process [ 12].

When Kpn00632 is expressed in E. coli, 5-fluorocytosine becomes toxic as exhibited by the substantial retardation of growth.

Importantly, mice xenografted with orthotopically placed human cancer cells exhibited substantial retardation of tumour progression with anti-S1P mAb treatment.

However, to our knowledge, no health authority feels confident that earlier detection of influenza by 1 to 3 weeks would necessarily lead to better control or substantial retardation of an outbreak.

At neutral pH (pH 7.4), RNAs were firmly incorporated with CaP-HDz-NCs, showing substantial retardation of RNA release; however, significant RNA release (52.8 ± 1.3%) was observed at slightly acidic pH (5.0 or 6.0 pH), implying that the NFs can release RNAs in acidic intracellular compartments such as endosomes (pH ∼5.0) and lysosomes (pH ∼4.5).

Very recently, Pouyssegur and coworkers have reported that the simultaneous invalidation of CA IX and CA XII using short hairpin RNA technology led to a substantial growth retardation in transfected LS174T colorectal cancer xenograft models, whereas the individual knock-outs yielded a substantially lower tumour growth retardation (Chiche et al, 2009).

A new phenazine-1-carboxylic acid phenylamide (PCA-1-P) exhibited substantial growth retardation of three gram-positive and the strong inhibitory activity of PCA-1-P derivatives towards the RNA synthesis in vitro T7-RNA-polymerase [ 16].

At the first evaluation, auxological data showed that all patients presented with substantial growth retardation at the time of 9p trisomy diagnosis for height (from -3.0 to -3.8 SDS), whereas the BMI was in the normal range (from 0.0 to -0.9 SDS).

All patients presented with substantial growth (height) retardation at the time of 9p trisomy diagnosis (from -3.0 to -3.8 SDS).

The impact energy, crack length and load level had a substantial effect on the retardation of crack growth.

For example, a recent investigation into DNA variants causing X-linked mental retardation included substantial amounts of sequence information on the coding regions of X-linked genes [Tarpey et al., 2009].