Sentence examples for substantial repression of from inspiring English sources
Substantial repression of FZD5 mRNA was confirmed for all five constructs with most efficient repression detected with constructs FZD5-2, FZD5-4, and FZD5-5.
People can tolerate long-term (months and years) treatment with glucosidase inhibitors under conditions where there is substantial repression of the ER enzymes.
Substantial repression of Dicer protein was observed under hypoxia but there was no significant alteration in hypoxic repression of Dicer protein after HIF-1α RNA interference.
Our observation that there is a substantial repression of gene expression in the fat body post-mating may reflect that there is a decrease in fat body tissue in the head post-mating.
Knockdown of p53 resulted in the significant repression of miR-509-5p miR-509-5p miR-509-5p overexpressinn of p53 resulthe in a substantial inducells of miR-509-5p expression in all cell lines.
Despite substantial repression and activation of the wild-type (WT) sensor by miR-130a mimic and inhibitor, respectively, the seed-matching region mutant sensor remained unresponsive.
Perhaps most importantly, this approach aligns with the goals of a biologist considering the top-ranked predictions in an attempt to focus on those most likely to undergo substantial repression.
However, five exceptional fertile lines of outbred XY females were generated by the Cattanach laboratory; all had deletions in the Y chromosome short arm (Yp) between Sry and the centromere that resulted in a marked reduction in gene copies within the Rbmy cluster and substantial or complete repression of Sry transcription (Capel et al., 1993; Laval et al., 1995; Mahadevaiah et al., 1998).
These results could be explained by a bystander effect, with regulation (activation and/or repression) of a substantial number of genes at lower absorbed doses with origin in non-irradiated cells.
This indicates that stronger hnRNP C binding and hence stronger repression of cryptic Alu exons provided a substantial fitness benefit during primate evolution, and that accidental Alu exonization imposes a significant cost to survival.
Although mitochondrial dysfunction provoked a substantial decline of IRS-1 mRNA as shown in Figure 3A B, posttranscriptional repression of IRS-1 should not be excluded.
