Sentence examples for substantial repression from inspiring English sources

Despite substantial repression and activation of the wild-type (WT) sensor by miR-130a mimic and inhibitor, respectively, the seed-matching region mutant sensor remained unresponsive.

Substantial repression of FZD5 mRNA was confirmed for all five constructs with most efficient repression detected with constructs FZD5-2, FZD5-4, and FZD5-5.

shaker, a voltage-gated cation channel, is among the genes that show the most substantial repression post-mating (2 FC; FDR rank 45).

People can tolerate long-term (months and years) treatment with glucosidase inhibitors under conditions where there is substantial repression of the ER enzymes.

Substantial repression of Dicer protein was observed under hypoxia but there was no significant alteration in hypoxic repression of Dicer protein after HIF-1α RNA interference.

Perhaps most importantly, this approach aligns with the goals of a biologist considering the top-ranked predictions in an attempt to focus on those most likely to undergo substantial repression.

Knockdown of p53 resulted in the significant repression of miR-509-5p miR-509-5p miR-509-5p overexpressinn of p53 resulthe in a substantial inducells of miR-509-5p expression in all cell lines.

However, five exceptional fertile lines of outbred XY females were generated by the Cattanach laboratory; all had deletions in the Y chromosome short arm (Yp) between Sry and the centromere that resulted in a marked reduction in gene copies within the Rbmy cluster and substantial or complete repression of Sry transcription (Capel et al., 1993; Laval et al., 1995; Mahadevaiah et al., 1998).

Second, a substantial fraction of the repression response initiated by MYCN-ER activation occurred as rapidly as the earliest induction response.

Thus, IRES-mediated translational stimulation in mitosis may occur, but is likely to be relatively minor compared to the substantial gene-specific translational repression that we identified in this study.

However, these authors also found that the H3K4me3 levels increased at the 5′ ends of a substantial number of diamide-repressed genes during their repression, including RP genes [ 63], which clearly contradicts our results.