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In contrast, the CDR3 loop appears highly flexible and mobile and undergoes substantial repositioning upon binding the p/MHC complex.
Spadafora [ 36] also hypothesized that L1 RT could be implicated in the substantial repositioning of chromatin in the nuclei and, therefore, in the modulation of expression of other genes.
We expect that some conformational changes from the existing crystal structures of both Wpl1 and Smc3 might be required for full engagement of all three sites, and it is tempting to speculate that Wpl1 motif 2, located on the protruding basic helix in the N-terminal lobe of the protein, might undergo substantial repositioning upon binding to Smc3.
Similar(57)
Dan Klores was repositioning himself.
There is repositioning.
Regular repositioning.
b Acquired after repositioning.
Reconstructive surgeries ensure adequate anatomical repositioning.
Repositioning along with herniotomy was performed.
c Acquired after repositioning with color Doppler.
Orbital reconstruction is performed before OZC repositioning.
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