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In this model, only prior domain knowledge and Gf showed substantial regression weights, whereas interest (AIST) did not significantly predict CPS.
This result represents the fastest and most substantial regression of atherosclerosis seen in a murine model after reduction in plasma cholesterol.
In summary, expression of LDLR via injection of AAV8.TBG.mLDLR induced marked reduction in cholesterol and substantial regression of atherosclerosis over 2 months as assessed by 2 independent methods of quantification at 2 different sites within the aorta.
Also, pioglitazone caused substantial regression of carotid IMT from baseline (p < 0.001) [ 89].
There was substantial regression to the mean for all three cognitive function tests.
The effect of the baseline cognitive function measures (b < 1.00) indicated substantial regression to the mean.
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The virus was also able to induce substantial regressions of these human adenocarcinomas engrafted in nude mice.
This approach is clearly evidence-based, as a number of studies have documented substantial, however variably strong, regression of LVH with various antihypertensive drugs [ 5].
Optimized schedules lead to substantial cancer regression even with relatively low drug concentrations.
Previous work carried out in transgenic EGFR and ERBB2-mutant mice showed substantial tumor regression when mice were treated with a combination of BIBW-2992 and rapamycin targeting mTOR (or more specifically TORC1) [31], [31].
The lack of substantial dilution (regression slope of −0.34; Figure S2A, Table S4B) of CAND in CSE and PI samples with increasing discharge is not clear.
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