Sentence examples for substantial refinement from inspiring English sources

Because the diagnosis of concussions has undergone substantial refinement since the 1960s and 1970s, when many of the survey respondents had played, a modern description of symptoms -- such as nausea or seeing stars following a strong blow to the head, not simply being knocked unconscious -- was provided.

Substantial refinement of the item set was required to establish a consistent model, and a second sample (n = 883) was surveyed to replicate the model.

The negotiations commonly involved an iterative sequence of discussion and deal changes, frequently involving substantial refinement of the nature of the potential deal as discussions within the acquiring firm proceeded.

However, the current consensus (e.g. Fortnow 2009) is that these approaches are still in need of substantial refinement or that genuinely new methods will be required in order to yield the desired separations.

Size exclusion chromatography afforded a facile approach to quantify the mass of the unattached polymer, and provide a substantial refinement to estimates of chain graft density beyond traditionally-used approaches, such as thermogravimetry.

Application of the conditional Granger analysis resulted in a substantial refinement of the plasticity pattern provided by PGC.

Since substantial refinements in the isolation, expansion and transplantation of chondrocytes have been made in recent years, the treatment of early stage osteoarthritic lesions using ACT might now be feasible.

We note that the justice committee in its recent report argues that the proposals were in need of "substantial further refinement".

This process induced substantial grain refinement in the coarse-grained casting leading to a grain size of approximately 50 nm.

The substantial grain refinement of aluminum matrix as well as significant size reduction of B4C particles was observed in the weld nugget.

Sabir et al. (2001) pointed out that there is a strong evidence that MK significantly influences the pore structure in pastes and mortars and produces substantial pore refinement leading to significant modifications to the water transport properties.