Sentence examples for substantial recent progress from inspiring English sources

Substantial recent progress has been reported in the context of implementing 'personalized' cancer medicine, informed by tumor genotyping.

Although substantial recent progress has been made in identifying genetic factors, the pathophysiology of the disease remains a mystery.

On the contrary, substantial recent progress in the positional cloning of genes influencing such complex phenotypes suggests that modern approaches based around a family-based linkage paradigm will be successful.

There has been substantial recent progress in using mathematical modelling methods to understand aspects of the epidemiology of pertussis infection [ 19– 22], including how natural immunity may underlie long-term trends [ 19], and how changes in the duration of vaccine-induced and natural immunity can account for trends in incidence [ 20].

There has been substantial recent progress in our understanding of the molecular mechanism of oestrogen action, most particularly by the discovery of (i) a second ER (ii) the role of co-repressors/co-activators (iii) the importance of conformational change of ER.

The present article attempts to step inside the broader physiological roles of NO and, taking advantage of the substantial recent progress in understanding the cellular and molecular mechanisms it engages, to start to build a picture of how it operates as a signalling molecule.

While this was a positive development, he added, "a substantial portion of the recent progress…has been concentrated in near-term budget changes, which, taken together, could create a significant headwind for the economic recovery".

However, a substantial portion of the recent progress in lowering the deficit has been concentrated in near-term budget changes, which, taken together, could create a significant headwind for the economic recovery … Moreover, besides having adverse effects on jobs and incomes, a slower recovery would lead to less actual deficit reduction in the short run for any given set of fiscal actions.

He then argued that given the state of the economy, we're currently spending too little, not too much: "A substantial portion of the recent progress in lowering the deficit has been concentrated in near-term budget changes, which, taken together, could create a significant headwind for the economic recovery".

However, the production of plasmids encoding TALENs still requires substantial bench work, despite recent progress (Cermak et al., 2011), tempering enthusiasm for this option, at least in its current state.

However recent progress has been substantial and we now know that the distribution of non-synonymous mutational effects is very leptokurtic and spans many orders of magnitude in many different species [ 46, 47, 110- 112].