Batch effects and differences in sample preparation can have substantial ramifications on the outcomes.
At the same time that Clarke relinquished his selectorial powers, Darren Lehmann was appointed coach, a move that had substantial ramifications for the wisdom of Clarke's decision.
The Court's ultimate decision in this case will have substantial ramifications for seamen, who face substantial risk and hardship in their daily lives and rely on the "ancient duty" of shipowners to provide them with maintenance and cure.
If the power is significant and will have substantial ramifications and consequences for the way the regulator behaves, the content of the code and the way it is enforced, we should look at it very carefully.
The two sides were said to be exchanging proposals and counterproposals late Tuesday in a showdown that could have substantial ramifications for national security policy and the political climate heading toward Election Day.
All of these findings have substantial ramifications for the rehabilitation of aquatic ecosystems in Jinan City as a reference for river ecological remediation in rivers with scarce ecological data worldwide.
Whatever your view of the situation (mine is below), the vote and resulting funding cuts will have substantial ramifications for important programs aimed at limiting risks to vulnerable populations in hazard zones.
Email hell is a common complaint for, well, basically every single user on Facebook, Twitter, LinkedIn or anywhere else people can speak publicly to any kind of network, and any attempts to tackle that — that work, at least — could have pretty substantial ramifications.
These trends have substantial ramifications on overall costs incurred by the older adult population.
So it's essential that workers are classified and paid properly to avoid substantial financial ramifications.
Since the failure of CPB structures can have substantial financial ramifications and cause severe injuries and/or fatalities (Nasir and Fall 2009), mechanical stability has been considered as a significant design criterion of CPB structures.
