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Lauer's first substantial questioning of Clinton zeroed in on her use of a private email server while she was secretary of state, and the first audience question (pre-selected, presumably, by NBC), also asked Clinton about her emails.
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Therefore, we determined the stoichiometry of FtsZ and ZapA in vivo and the interaction with FtsZ in vitro at pH 7.5 and 6.5 and discovered that the His tag had a substantial effect, questioning previous studies done without removing the His tag (25, 27, 28).
"I am not questioning whether a substantial proportion of veterans of Desert Storm have symptoms related to their service," Dr. Bailar said in an e-mail.
Since Sen. Cruz (R-Texas) announced his candidacy two weeks ago with the words "God isn't done with America yet," a substantial number of Americans "have begun seriously questioning the existence of God," said Carol Foyler, the executive director of the American Society of Atheists.
Moreover, ingestion of an energy drink was associated with a substantial drop in cerebral blood flow, hence critically questioning the manufactures promotion about a better mental profile.
With almost every public poll showing him trailing by a substantial margin, though Mr. Bradley escalated his attacks to their toughest level yet by questioning Mr. Gore's electability, an explosive issue that until now Mr. Bradley has left to his followers.
Our previous study already demonstrated substantial sequence changes along the East African cichlid phylogeny for the aromatase cypa9a1A gene, questioning its function and hence its indispensability for sexual development in fish (Böhne et al. 2013).
In our opinion, substantial improvement is not to be gained by introducing yet another transaction model, but by questioning the basic paradigm of transaction processing itself.
He also argued there were "substantial challenges" with enforcing a ban on smoking in cars particularly vehicles "travelling at speed", questioning whether people would comply with the law if they knew there was little chance of it being enforced.
The creation of the new unit will formally strip the C.I.A. of its primary role in questioning high-level detainees, but agency officials said they would continue to play a substantial role.
The only existing randomized study questioning the optimal sequencing of radio- and chemotherapy in early breast cancer found no substantial differences in locoregional or distant recurrence between the treatment arms [ 1, 2].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com