Second, the way in which contacts are weighted or defined makes a very substantial difference to quantification of R0 and its components.
A human interpreter has excellent image comprehension and pattern recognition capabilities, but is prone to substantial variability in quantification tasks.
The city briefly tried to pull back from its 60-40 quantificatiof of "substantial portion," but a State Supreme Court justice warned its lawyers that they were bound by the definition they had given in federal court.
However, in recent years there has been substantial progress for absolute quantification of T1, T2, PD of a whole volume with high resolution in a mere 5 min [4, 5].
We devoted substantial effort to the quantification of binding affinities of the interactions using ITC.
However, 18S rRNA expression is monitored primarily to double check for substantial anomalies in mRNA quantification when positive results are found, rather than as a precise means of normalization for results which appear consistent.
An assessment of immunogenicity based on binding velocity on BIAcore chips, rather than on BIAcore response units at saturation, did not reveal a substantial difference for the quantification of mouse anti-fusion protein antibodies (Additional file 7).
Qualitative inter-observer agreement for the anatomical structures which met the criteria for quantification was also substantial (PABAK = 0.76).
Semi-quantitative immunofluorescence microscopy was employed to evaluate proteoglycan expression, due to its greater resolution (at essentially the single cell level) compared with biochemical procedures based on total cell protein, and in view of substantial technical obstacles to accurate quantification of large proteoglycan core proteins by techniques such as immunoblotting.
Hypoxia-sensitive PET tracers are slow to reach diffusive equilibrium in a substantial fraction of pancreatic tumours, confounding quantification of hypoxia using both static (TBR) and dynamic (k 3) PET imaging.
