Sentence examples for substantial purification from inspiring English sources

However, in order to acquire high quality spectra for structure elucidation, the NMR method requires relatively large amounts of pure compound (up to 100 µg), often requiring substantial purification from extracts or other mixtures of compounds.

It should be noted that low-speed direct centrifugation of the homogenates, while less efficient than gradients (which enriched the fusion protein up to 85% in a single density separation following cell lysis) was also able to effect substantial concentration and purification of Zera fusions (data not shown).

Meanwhile, the excellent productivity of two enzymes in one host would provide cost reduction in fermentation, purification, and substantial savings in energy consumption.

A noteworthy observation emerged from our purification was substantial interactions of H2A.Z nucleosomes with WDR5 and BPTF, which are known to interact with H3K4me tails and play important roles in regulating chromatin function [ 26- 28].

Despite the high incorporation of [18F]fluoride into [18F]BF4 − during the labelling reaction, a large proportion of the [18F]BF4 − was lost during this purification step, causing a substantial loss of yield.

Purification of legumin revealed substantial accumulation of the propolypeptide in SMARC1N-PN1.

Amplifications of selected loci used a lower concentration of dNTPs so that PCR products could be directly sequenced as purification methods resulted in substantial product loss and poor sequence quality.

While this represents a significant milestone, using adherent culture for milligram-scale purification of the receptor monomer poses a substantial challenge.

During the acute phase of their disease, a substantial number of patients are treated using extracorporeal blood purification devices.

As an initial purification step, the Phenylsepharose™ column achieved a substantial increase in protein purity to 25%, along with removal of most of the lipid.

In contrast, there was no appreciable enrichment of known DNA-interacting proteins of the mitochondrial nucleoid (TFAM or mtSSB) (Fig.  6B), confirming that a substantial enrichment of PolgA had been achieved by the affinity purification procedure.