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I am less convinced by the analysis of pain behavior and the efficacy of some of the techniques used here which raise substantial problems of interpretation.
This answered positively a problem raised by A.T.-M.
But there is another problem, raised by recent evidence.
The EU faces substantial problems.
There are substantial problems to solve".
Therefore, this approach may face substantial problems.
Despite the substantial problems identified, the team was disbanded.
There was a big problem raising money.
This problem raises questions of generalisability.
Though our results focused on a previously characterized CNV, they raise the possibility that there could be a substantial problem across unknown regions of the genome with common CNVs.
"It could become a substantial problem," he said.
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