Sentence examples for substantial problems for from inspiring English sources
There are some potential matchups that would pose substantial problems for the Spurs, but Popovich, Ginobili, Parker and Duncan alone give San Antonio ample in-series flexibility.
Taken together, this causes substantial problems for fully automatic pipelines that aim to use these data comprehensively for studies of animal phylogenetics and the molecular evolution of mitogenomes.
Much remains to be learnt about the strategies N meningitidis employs to evade aspects of immune killing, including mimicry of host molecules by bacterial structures such as capsule and lipopolysaccharide, which poses substantial problems for vaccine design.
For example, notification of security breach incidents poses substantial problems for U.S. businesses and will continue to do so as the frequency of breaches increases and American companies struggle to comply with a competing patchwork of state laws and regulations at home while facing growing pressure abroad from the EU for greater transparency.
Fine-grained, gritty ash caused substantial problems for internal-combustion engines and other mechanical and electrical equipment.
The repetitive structure of the rRNA operons causes substantial problems for genome assembly software [ 42].
The recovery of the otters proved not to be a substantial problem for the Navy.
From a global perspective, right now we are building up a huge problem in the west with our net debt and this is a substantial problem for development.
Because of the high cost of so many films, many studios have been eager to thwart film piracy, which is a substantial problem for American films in Asia.
Methyl mercury, the toxic form, even poses a substantial problem for the Arctic, she said, because it can accumulate in polar bears and seals.
"Discrimination continues to be a substantial problem for too many job seekers and workers, and we must continue to build our capacity to enforce the laws that ensure that workplaces are free of unlawful bias," the commission's chairwoman, Jacqueline A. Berrien, said in a statement.
