Sentence examples for substantial problems exist from inspiring English sources

However, while cloning is widely used in basic research, as well as in some biomedical and agricultural applications, a number of substantial problems exist with the current technologies, including relatively low success rates and severe defects of the fetus and/or placenta resulting in abortion, neonatal death and postnatal disease [ 2- 4].

Still, real problems exist.

Unfortunately, the vast majority of studies conducted in support of split-foveal processing fail to adhere to either of these requirements (for a description of the substantial problems that exist in previous research in this area, see [4], [5]).

Other problems exist as well.

acknowledging that such problems exist.

No such problems exist at Cornbury.

Problems exist in this jurisdiction too, however.

Allied has denied that such problems exist.

First, acknowledge that incentive problems exist.

However, problems exist.

Problems exist everywhere.