Sentence examples for substantial problem worldwide from inspiring English sources

Multidrug-resistant A. baumannii has emerged as a substantial problem worldwide (2 ).

During the last few years, A. baumannii has been increasingly isolated from severely ill patients, and its usual cross-resistance to most available antimicrobial drugs, including carbapenems, poses substantial problems worldwide and especially in the United States (1 ).

Asthma is a significant problem worldwide that causes substantial social impacts and costs to public and private health systems [ 1].

Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), are common clinical disorders and present substantial health problems worldwide [ 1- 3].

Chronic kidney disease (CKD) is an increasing public health problem worldwide, resulting in substantial morbidity and mortality related to cardiovascular disease and end-stage renal disease (Coresh et al. 2007; Meguid El Nahas and Bello 2005).

The number of people with IAP exposure worldwide continues to increase and remains a substantial problem in many developing countries, particularly in Asia and sub-Saharan Africa.

"It could become a substantial problem," he said.

"It's a substantial problem," Botstein recognized.

Corrosion of reinforcement steel forms a huge problem worldwide.

Aggressive driving is a growing problem worldwide.

Osteoporosis is a serious health problem worldwide.