Sentence examples for substantial problem to from inspiring English sources
The banks are the heart of the matter, and its the political power of the banks that presents the most substantial problem to this administration in terms of moving forward with sensible policies, says Johnson.
From computer simulations of metabolic reaction networks we deduced a set important aspects to be considered when interpreting partial correlation coefficients in reaction systems: (a) Metabolites in equilibrium due to reversible reactions can readily be recovered, whereas irreversible reactions pose a substantial problem to association-based reconstruction attempts (in concordance with [ 6]).
There are substantial problems to solve".
Mr Cameron and Mr Obama have substantial problems to discuss, such as when and how to withdraw troops from Afghanistan.THE TRIAL of Anwar Ibrahim, a former deputy prime minister of Malaysia and the most prominent figure in that country's opposition, resumes.
However this technique is still facing substantial problems to produce porous structure having sufficient mechanical strength.
Both case diseases are increasingly common and present substantial problems to health care agencies.
There are substantial problems to assay the sn-1 acylation activity of lysophospholipid acyltransferases because the sn-2 lysophospholipid substrates are unstable due to rapid acyl migration to the sn-1 position.
A substantial number of service users (but not carers) remained unconvinced that they had a substantial problem up to the point of contact with mental health services.
A substantial technical problem to identifying such sets is the astronomical number of possible combinations (triples, quadruples, and so forth) of reactions, which renders an exhaustive evaluation infeasible.
This failure causes a substantial problem when trying to estimate the overall rates of mental health problems.
Indeed, previous reports suggest that this syndrome is a substantial problem for up to 50% of high-yielding cows [ 12, 13] and, hence, hepatic lipidosis is recognized as a serious herd problem and animal welfare concern.
