Sentence examples for substantial problem that from inspiring English sources

However, poor compliance with therapy is a substantial problem that affects 20%to70%0% of the patients during follow-up [ 5- 16].

"It leaves a substantial problem that no one's sure how will be addressed," said one senator.

This 1928-31 edition was once lightly revised in 1974 by A. Henrichs, and today presents a number of substantial problems that need to be addressed.

Unfortunately, the vast majority of studies conducted in support of split-foveal processing fail to adhere to either of these requirements (for a description of the substantial problems that exist in previous research in this area, see [4], [5]).

The Moroccan subgroup of childhood offenders has substantial problems that might hamper healthy development.

Preterm birth (PTB) is a substantial health problem that accounts for significant infant morbidity and mortality and poses an economic burden to both individuals and the state of residence.

In order to preserve the Kansas law, he will have to show that noncitizen voter registration is a substantial problem and that nothing short of the state's proof-of-citizenship law can stop it.

Kobach, who was also on the voter fraud commission with von Spakovsky, has to show that noncitizens getting on the voter rolls is a substantial problem and that nothing short of asking people to provide proof of citizenship can prevent it.

And second, if there isn't, what steps need to be taken to rein in the substantial moral hazard problem that will therefore result?

The trade group study shows that tourism can drop off more sharply if terrorism is combined with substantial economic problems that directly impact the conduct of the tourism industry — but that is not the case in Turkey.

The proposal calls for the retailers to inspect the estimated 500 Bangladeshi factories that the North American retailers use within 12 months, and then develop plans to fix any substantial safety problems that are found.