Sentence examples for substantial problem in from inspiring English sources

Malaria remains a substantial problem in this region and efforts to minimise transmission should be considered in future house planning.

But, he warned, "It does leave us with a substantial problem in the next year -- as we have to make these major infrastructure investments -- about where we're going to get the capital".

Conclusions PPO use is a substantial problem in older surgical patients with HNC, one that warrants consideration of alternative treatment strategies and continued examination of prescription guidelines for patients with HNC.

Nitrogen (N) leaching is considered a substantial problem in South China vegetable production because of the heavy rainfall and the excessive application of N fertilizer, but quantitative data and effective countermeasures are lacking.

Harassment "is a substantial problem in New York City which 7A can be made to address very effectively," Paul A. Crotty, the city's former Commissioner of Housing Preservation and Community Development, told a State Senate committee investigating the practice late last year.

Low patient adherence is a substantial problem in therapy.

However, this technique still possesses substantial problems in-terms of poor surface finish and dimensional accuracy of the prototypes.

By 1956, Forrester was convinced that many substantial problems in computing had been solved.

By the mid 1960s, Mao was convinced that there were some substantial problems in China.

Borehole instabilities during drilling cause substantial problems in all areas of the world.

The task force's recommendations come two months after a separate Board of Education study found substantial problems in the bilingual education program.