Sentence examples for substantial predisposition from inspiring English sources

Rapid and inexpensive sequencing of genes can identify individuals carrying individually rare mutations that confer substantial predisposition to preventable diseases.

Gut inflammatory diseases such as IBD have been long known as having a substantial genetic predisposition component and a recent review of genome-wide scans reported on the seven confirmed and replicated cases of genetic susceptibility loci, with many more, however, that need independent confirmation and verification [42].

A complex segregation study conducted in the aborigines of Taiwan supported the existence of a substantial genetic predisposition to gout; however, no heritability estimate was reported.

There was no significant gender predisposition [ 74].

HLA undoubtedly plays a substantial role in genetic predisposition for NPC development.

Although the total number of AD risk genes remains elusive, there is good evidence suggesting that, in combination, they have a substantial impact on AD predisposition.

Substantial evidence suggests that genetic predisposition has a significant impact on individual susceptibility to AS [ 2].

The model predicts that alleles under sex-differential selection, including sexually antagonistic alleles, will disproportionately contribute to genetic variation for disease predisposition, thereby generating substantial sexual dimorphism in the genetic architecture of complex (polygenic) diseases.

It is likely that genetic predisposition plays a more substantial role in this group.

Although ~75% of colon cancer cases are sporadic, familial predisposition occurs in a substantial percentage of cases (Burt, 2000).

8 The genetic predisposition is strong.