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This finding has implications for managing PNs in the community; because the risk of cancer is substantial, patients should be managed based on their individualized risk of malignancy.
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Year 4 and year 6 students would have had substantial real patient encounters.
Nonelective colorectal surgery is associated with substantial patient morbidity and mortality.
But by adopting an "any-patient-to-any-bed" approach we were able to largely eliminate the need for traditional triage, except during periods of substantial patient surge.
Despite use of this strategy, the postthrombotic syndrome (PTS) develops frequently, causes substantial patient disability, and impairs quality of life.
But that relatively straightforward picture is clouded by the substantial patient-to-patient variations.
The total exam time of about 40 min ensures a substantial patient throughput and first diagnostic findings are encouraging.
Bone and joint disorders impose an enormous social and economic burden on society, causing disability and substantial patient morbidity.
Best scientific practices, as described in the FDA PRO Guidance [4], were followed throughout the development of both PROs, including an iterative development methodology and substantial patient input.
Although the approval rate of new TKIs is high and substantial patient benefit is achieved, there is a lack of long-term efficacy in certain patients with RTK-driven tumors.
This is likely to translate into substantial patient benefit.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com