Sentence examples for substantial pathological changes from inspiring English sources

Thus, although the possibility that contusion in the unilateral cerebral cortex might affect the severity of histological changes and the levels of gene expressions in the contralateral cortex and the thalamus could not be ruled out, substantial pathological changes were observed in the aged brain due to PGRN deficiency.

We cannot, however, rule out that cortisol measured at other time points during the day, as in the evening, could be affected in this patient group, but the data on CAR does not implicate any substantial pathological change in the basal non-stimulated HPA activity.

The rest of skeleton was without significant pathological changes.

Therefore, we suggested that if the femoral remnant was viable and did not display any pathological changes that might have caused its weakening, then biomechanical factors played a substantial role in the pathogenesis of those fractures.

Pathological changes were found in all patients.

Pathological changes in organs were scored.

Pathological changes in these organs disrupt behavior and retard larval growth.

Pathological changes include demyelination, axon loss and mild gliosis.

No pathological changes were found on the periimplant tissues.

However, the pathological changes of muscular tissue are less specific.

No pathological changes were observed in the sham group.