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Seven of the nine APNs showed substantial or modest upregulation from 3 hpi to 12 hpi.
Outcomes of pregnancies among women affected by major depression during pregnancy were worse than in unaffected women, but smoking during pregnancy made a substantial or modest contribution to the increased prevalence of SGA, LBW, preterm birth and admission to a neonatal unit associated with depression during pregnancy.
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Despite these substantial alterations no, or modest, changes were observed in mature microRNA production.
Importantly, it should be noted that the effects of pharmacologic agents on stiffness are usually slight or modest, but not substantial.
Given that most treatment effects are relatively small or modest, 13 relative changes of 1.10-fold can be considered large and of 1.20-fold can be considered substantial.
Smoking during pregnancy made a substantial to modest contribution to adverse outcomes associated with depression during pregnancy.
The contribution of smoking was substantial to modest for small-for-gestational age newborn (<−2 SD below mean birth), low birth weight (<2500 g), preterm birth (<37 weeks) and admission to neonatal intensive care associated with major depression, whereas SES made only a minor contribution.
Just wear modest clothing or modest swimwear.
Opt instead for simple or modest outfits.
In fact, America's aging, though substantial, is relatively modest compared with that of many European countries and Japan.
The changes -- some in words, some in deeds; some substantial, some fairly modest -- have been enough that many community leaders now talk of a quiet revolution in Soundview.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com