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The dataset is, however, suitable to detect responses common to all – or to a substantial number of – pathogens, or to reflect the "acute phase response" in the lung.
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Despite effective control of many of the deadly infectious diseases by vaccination, there remain a substantial number of important pathogens for which there exists no effective preventive tool based on immunization.
On the other hand, when increasing the cefepime MIC cut-off to 8 mg/ml, T>MIC decreased to ≤67% at the first dose and <44% at steady state, indicating that the dosage would be inadequate in a substantial number of patients infected with Gram-negative pathogens with such borderline susceptibilities, as suggested by Bhat et al. [ 6].
Similar to wounds, microbiology from upper and lower respiratory tracts revealed a variety of common but also uncommon pathogens, including a substantial number of highly resistant species.
The substantial number of patients with encephalitis identified through this project enabled robust pathogen-specific case series of well-established but relatively rare causes of encephalitis.
Hence, we expect a substantial number of interactions to predict homologous counterparts in more tractable experimental systems as well as in other pathogens.
A substantial number of fatalities occurred in businesses.
Still, a substantial number of Americans are not convinced.
There are a substantial number of unnecessary urine culture requests.
A substantial number of bioaccumulation fish tests are conducted regularly.
There were still a substantial number of walkouts.
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