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And the result is a very substantial spike in prices with fairly substantial negative consequences to the economy.
Alan Greenspan worried this week about low oil stocks and the "substantial negative consequences" of high oil prices.
While the NAFTA and World Trade Organization treaties have helped to expand overall U.S. economic growth, many economists argue they have had substantial negative consequences for American workers.
Despite the above positive descriptions, about half of the participants also expressed substantial negative consequences of being diagnosed with ADHD.
Here, we demonstrate that a correlated response to selection (reduced larval size) may occur relatively quickly and may have substantial, negative consequences for survival of larvae and juveniles.
If letting a patient decide clearly has no substantial negative consequences, then health workers should focus on neutral communication, even when they have reason to doubt that the patient is autonomous.
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In the case of mammography screening, studies have shown that the receipt of a false-positive result has substantial negative psychosocial consequences for women.
However, increased production has come at the cost of substantial negative environmental consequences.
A poll of economists by the Centre for Macroeconomics, conducted before the referendum, found that more than 80% agreed that there would be substantial negative long-term consequences for the UK's financial sector following a Brexit.
Given well-known U.S. national security concerns about Huawei and other Chinese telecommunications companies, a shift to Chinese dominance in 5G would have substantial negative national security consequences for the United States".
It seems to us that there is little to no question that if the Ryan Plan were adapted it would mean dramatic changes to the way Medicare is delivered and would apparently have substantial negative cost and coverage consequences for many beneficiaries.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com