Substantial tumor multiplicity was found, but K-ras and p53 gene mutations were virtually absent.
By implication, variants with such profiles are likely to collectively confer substantial risk because of their multiplicity or sub-maximal LD with tagging SNPs.
This multiplicity of material is to be welcomed.
If a multiplicity of peptides still induced substantial CTL responses without significantly compromising viral fitness, there may be a high genetic barrier to abolish CTL recognition.
The public interests in protecting access to television for the millions of homes without cable and in assuring the availability of "a multiplicity of information sources" are unquestionably substantial.
In all cases, the multiplicity of samples requires access to substantial computational and storage capacities.
That sense of multiplicity is still strong.
The meaningful findings (increasing trends and age patterns), the multiplicity of data sources, the use of validated registries and the substantial coverage of the population provide some evidence that health administrative databases and the selection of 16 prevalent conditions are useful for measuring and monitoring multimorbidity in Ontario population.
The work here has only touched on the full content of even this small metabolic model simply exploring the appropriate cellular context by varying bath metabolite pool sizes, and potential multiplicity of fixed points by varying initial internal metabolite concentrations, generates a substantial quantity of data requiring significant analysis effort.
Yet the will is there to grasp the opportunity.Europe's misgivingsBy contrast, America's relationship with Europe expressed not just in NATO but through a multiplicity of trading, investment and intelligence ties, as well as common values is undoubtedly substantial.
The multiplicity of available applications to predict transcription factor binding sites in a particular locus contrasts with the substantial computational expertise that is demanded to manipulate them, which may constitute a potential barrier for the experimental community.
