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The main substantial modification to the protocol was approved in October 2011, following DAA withdrawal from the market.
The general architecture of GEOSTAR demonstrated its validity during the Adriatic Sea mission and consequently no substantial modification to the concept is foreseen.
29 The Deepening our Understanding of Quality in Australia (DUQuA) study involves substantial modification to the DUQuE study design, to advance the international evidence base.
Currently, these methods can not be reproduced directly within an i2b2 hive without requiring substantial modification to the underlying code (potentially developing a new cell).
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Substantial modifications to the original SNO detector are being effected in order to achieve this.
If necessary, the public inquiry could be suspended for up to 6 months in order to make substantial modifications to the project file submitted during the inquiry.
Then, it can ensure an easier integration of new modules, but also an increased possibility of applying also substantial modifications to the platform.
However, it suffers from relatively low production rates and poor control of fiber alignment without substantial modifications to the fiber collector mechanism.
It has been shown that both R1234yf and R1234ze(E) can be substituted for R134a with comparable performance and no substantial modifications to the original system.
Finally, besides making substantial modifications to the CTSiM environment by adding new interfaces and tools, we have been working to design adaptive scaffolding that takes into account how students use the different tools and combine information from the different interfaces.
We recognize that software packages may be designed to do these preparation steps as well as more major modifications spelled out in Step F. However, patients who require substantial modifications to the anatomy captured in the medical images should be considered in Group II: Modified Anatomical Models.
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