Heterogeneous catalysts are complex and substantial new methodology developments have been needed in each of these areas.
Substantial statistical methodology has been dedicated to overcoming this problem including replication, cross-validation, limits for family-wise error rates and Bonferroni-adjustment for multiple testing [ 14, 15].
However, these studies have substantial differences in methodologies and definitions of target groups.
The handling of uncertainty in health economics is used as a point of reference for addressing the uncertainty in a BIA, as a substantial number of methodologies have already been developed for CEA that may be applicable for BIA.
The new clustering methodology offers substantial improvement over the previous methodology, as it is unambiguously actionable and produces superior results.
MB made substantial contributions to methodology and drafted sections of the manuscript.
One comparative analysis of four selected partnership analysis tools was excluded due to a substantial gap in methodology documented [ 63].
In this review we did not make a distinction between the two methods because there is substantial overlap in methodology.
Substantial differences in methodology, scope, and data sources often make comparison between the studies reviewed difficult, and the depth of research varies widely across the four impact areas.
As a result, substantial improvement in methodology would require concerted, long-term actions with interdisciplinary collaborations among scientists, engineers, medical researchers, and practitioners.
Indeed, it is very difficult to compare our results with those of other studies, given substantial differences in methodology and, actually, there is not even a universally accepted definition of a chronic disease.
