Sentence examples for substantial methodological challenges from inspiring English sources

The purpose of this paper is to achieve a conceptual consolidation of Adaptive Foresight, to review in a fairly hands-on way methodological experience thus far, and to outline the substantial methodological challenges ahead.

The presence of multiple, often similar alleles that commonly cannot be assigned to loci and must be genotyped simultaneously poses substantial methodological challenges [ 38].

Furthermore, evaluating the impact of these changes also present substantial methodological challenges, requiring a 'deep understanding' of the context and complexity of the problems that eHealth interventions attempt to address [ 57– 57].

As already mentioned, blinding constitutes a substantial methodological challenge in rTMS studies.

Limited standardisation in defining injuries has repeatedly been reported as a serious methodological pitfall when comparing study outcomes [ 13, 31] and has been identified as a substantial methodological challenge for future studies [ 32].

This added complexity poses significant methodological challenges.

This poses significant methodological challenges.

There are significant methodological challenges in validating FMEA.

Whereas there is no doubt that these indirect costs can pose a substantial burden on households, there are numerous methodological challenges in measuring this burden adequately; these challenges have been discussed in detail in a previous study [ 59].

Less concerned to relate Darwin to prior philosophical traditions, the first major interpreter of Darwin's theory for the German-speaking world, the paleontologist Heinrich Bronn (1800 62), was responsible for a sympathetic, but critical reading of Darwin that challenged his theory on substantial methodological and empirical points.

Although most of the models have potential to predict future trends depending on how the model is populated, the methodological challenges are considerable, and there is substantial need for further research and development.