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This approach provides a substantial mechanism for embedding scholarly practice as an action of engagement in open and participatory environments, with a focus on best practice, rather than avoidance of plagiarism.
However, the substantial mechanism should be further investigated.
However, further functional studies should be performed to elucidate the substantial mechanism.
Loss of responsiveness to the growth inhibitory effect of TGF- β is a substantial mechanism in cancer development (Moses et al, 1987).
Compensation is discussed as a substantial mechanism to prolong the preclinical phase not only in HD mutant gene carriers but also in preclinical subjects at risk for other neurodegenerative diseases as well.
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In the present study, we have clarified for the first time that miR-146a-mediated suppression of ErbB4 is a substantial causal mechanism of Dox-induced cardiac toxicity.
In the present study, we have revealed for the first time that miR-532-3p-mediated miR-532-3p-mediated miR-532-3p-mediated miR-532-3p-mediated-induced cardiac toxicity.
Although heritability is substantial, genetic mechanisms predisposing to obesity are not very well understood.
Instead of imposing strict safety limits on forces and moments transmitted from the foundation onto the soil (aiming at avoiding pseudo-static failure), the new dynamic approach "invites" the creation of two simultaneous "failure" mechanisms: substantial foundation uplifting and ultimate-bearing-capacity slippage, while ensuring that peak and residual deformations are acceptable.
Although ameliorating these deficits would be of substantial benefit the mechanisms that underlie them are poorly characterized.
Despite the somewhat superficial comments one sometimes hears about 'fishing expeditions' and 'non-replication', in fact we are learning some substantial biology and mechanisms from these studies, and the replication of some markers across multiple studies is actually rather impressive [ 9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com