Major order disagreements were found on BTA19, where a substantial marker gap at the proximal end of the chromosome prevented alignment of the RH and linkage maps.
Significantly lower serum levels of serum NO metabolites in patients with acute ischemic syndromes are a marker of substantial endothelial dysfunction with consequent impaired coronary perfusion.
Considering the informative results of these recent trials, MET-PET might have substantial reliability as a marker of tumor biological characteristics, as well as a valuable impact on visualizing the tumor-invasive area of malignant glioma.
These data have been consolidated in two recent large meta-analyses also showing a substantial safety on markers of mineral bone disease (MBD) of this therapy [ 70, 71].
In the same cohort, we have previously established substantial differences in markers of systemic oxidative stress between patients and controls [ 31].
Although EGFP-LC3 is a marker of autophagosomes, a substantial fraction of the protein is often present in the nucleus as well [17], [18], [19], [20], [22].
Over a complete treatment course, 40 100 % of patients are reported to show a rise in ST, and failure to reach a substantial ST increase may be a marker of lack of efficacy [ 9, 22].
It therefore appears necessary to draw a clear distinction between the validity of plasma osmolality as a marker of acute and substantial body water loss, and its usefulness in differentiating between the LD and HD in less extreme environments.
Moreover, looking specifically at NK cell markers, we found substantial downregulation of both CD117, a key marker of immature NK cells, and of granzyme-K, a cytotoxic component of CD56bright NK cells, thereby confirming our flow cytometry results (Fig. 1) (Table S2).
The substantial upregulation of antioxidant enzymes and UCP3, a marker of mitochondrial energetics, may be a protective response to the heightened oxidative damage within the CR females.
