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As predicted, NOS3 and STAT3 transcription responded in a time-dependent manner with significant and rapid upregulation 15 min after TSA treatment followed by substantial long-lasting downregulation.
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The consequences of inaction on climate change are foreseeable, and doing nothing will result in real, substantial and long-lasting harm to the public.
In European countries, unemployment benefits are typically substantial and long-lasting.
In PD, cell replacement strategy has been based on the idea that neural graft-induced restoration of dopamine neurotransmission in the striatum could lead to substantial and long-lasting functional recovery.
The decision to raise the alert level to 7 from 5 on the scale amounts to an admission that the accident at the nuclear facility, brought on by the March 11 earthquake and tsunami, is likely to have substantial and long-lasting consequences for health and for the environment.
The economic benefits of such an approach are expected to be substantial and long-lasting.
Not only is this likely were widespread flooding to occur for any reason, but the damage done would be substantial and long-lasting, since London's stations have taken no precautions against it.
A substantial and long-lasting deviation toward the ipsilesional side was observed in lesioned rats.
Following the end of ethanol exposure (P30), neocortical development and plasticity may be further disrupted as a result of substantial and long-lasting alterations of CREB activity [70] [73], NMDA receptor activation [10], [26], and GABAergic mediated inhibition [24], [25], [74], [75].
Undoubtedly, Teh's thoughts and findings will continue to have substantial and long-lasting impacts on HTLV-1 research.
"With over 300 IKEA stores and many millions of customers joining the movement for children's education, we can make a substantial and long-lasting impact on children's lives.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com