Sentence examples for substantial leading from inspiring English sources

He dismisses substantial leading roles in the three plays previously mentioned.

But at the same time, an extraordinary pool of black acting (and directing and writing) talent is out there -- and substantial leading roles for them are still scarce.

Locally, these decreases could be substantial, leading to a reduction in the likelihood of occurrence from 40% to 1%.

Consequently, conducting analyses of actual ovulation order required a reduction in sample sizes that was sometimes quite substantial, leading to lower power.

Nonetheless, the results shown in this paper are substantial, leading us to believe that significant improvements can be derived from human-aware motion planning.

Despite the large varietal range in uptakes, variation between replicates was substantial leading to large LSDs, and very few varietal differences in Fig. 2a were statistically significant.

The industry in recent years has undergone substantial consolidation, leading to the mergers of United and Continental in 2010, Delta Air Lines and Northwest in 2008, and Southwest Airlines with AirTran in 2011.

It is therefore no coincidence that the number of New Chemical Entities reaching the market has also suffered a substantial decrease, leading to a productivity crisis within the pharmaceutical sector.

New releases continued into late 2006, at lower prices with more substantial content, leading to a better reception in the gaming press.

However, CT has substantial drawbacks leading to an almost complete replacement of this imaging technique by US and MRI.

These zinc-coordinating interactions appear to provide substantial stabilization leading to the packing of the monomers in the crystallographic dimer as observed here.