Sentence examples for substantial issue when from inspiring English sources

Since literally every individual in his or her life is likely to somehow depend upon medical care, the challenge of cultural diversity and intercultural understanding in this context is a substantial issue when talking about international stability at the individual and societal level.

Long- and very-long-chain fatty acids are hydrophobic and therefore pose substantial delivery issues when performing labeling studies in whole animals.

The high dropout rates associated with the online practice test indicate that substantial issues were experienced when engaging with the online environment in an assessment context.

The court is often asked to intervene at the last minute in death cases, and does so infrequently, and only when the justices think the case raises a substantial issue.

When assessing imported malaria cases, underreporting is a substantial issue.

The player, Muhammed Lasege, a 6-foot-11 native of Nigeria, won an injunction against the N.C.A.A. when Judge Geoffrey Morris ruled that Lasege had raised a substantial issue as to whether the N.C.A.A.'s decision on his eligibility was arbitrary.

"So when you have 500 or 1,000 people who are misallocated, it's a fairly substantial issue.

Not a truly substantial issue, but it bothered me.

Second, data provenance is another substantial issue in predictive toxicology.

indicated this loss of information is not a substantial issue.

"But there's a substantial issue about my client's mental state".