Sentence examples for substantial issue that from inspiring English sources

Nevertheless, transferability among populations is still a substantial issue that requires intensive study.

Prior reaching a final decision about the manuscript, we need to consider your response to address the following substantial issue that emerged from those discussions: Docking calculations were used to thoroughly sample association modes between two proteins and identify ensembles of low energy poses.

The goal this week is to find a formula for all those substantial issues that embraces a way out of the settlement dilemma, officials said.

There are significant and substantial issues that can and should be improved.

The specific question presented to the court was: Are post-traumatic stress disorder and bipolar disorder substantial issues that a military judge must consider before accepting a service member's guilty plea, when those disorders may have contributed to the charged misconduct?

For each of the five properties, a judgment is made and documented regarding whether there are substantial issues that decrease the confidence rating in each aspect of the body of evidence for the outcome.

Snoring from any position might indicate apnea or other significant issues that will require more substantial medical treatment to address.

The large number of motor vehicle insurance claims in the jurisdiction studied (about 14,000 per year in NSW) indicates a substantial public health issue that requires careful consideration to reduce the health, social and economic impact.

Despite its advantages, NC-OFDM possesses several substantial technical issues that need to be resolved in order to make this form of wireless data transmission within a DSA environment a viable option.

This also means that the material sometimes is ambiguous, sometimes because of semantic issues but also because the respondents were ambivalent about the substantial ethical issues that were discussed.

A timely and accurate problem list should improve patient safety, an important and timely issue that has received substantial attention since the 1999 Institute of Medicine report [ 85].