Sentence examples for substantial issue for from inspiring English sources
Lingering uncertainty over changes to capital requirements and regulatory structures are a substantial issue for investors to consider, but Jason Goldberg, the large- and mid-cap bank analyst at Barclays Capital, says that isnt a reason to avoid the sector altogether.
This is not a substantial issue for linear normalization, which is mostly driven by a large contrast change at the outside boundary of the brain, but the blurred internal structures could easily confuse high-dimensional non-linear registration [21].
Our rigorous evaluation of transmission linkage reduced potential misclassification of over a quarter of seroconversion endpoints – a substantial issue for efficacy trials of interventions to reduce HIV-1 infectiousness.
Ascending with the majority, he avoided the substantial issue of Iraq, and addressed the need to get the best armor for the soldiers already there.
"I think that's a welcome step, but it seems a little bit late in the game to be developing principles on this substantial issue and priority for American businesses, for labor, for faith communities, for law enforcement communities," he said.
There are of course still substantial issues unresolved for these polymorphisms too.
Illicit drug use for recreational purposes is a substantial issue within Western society and causes significant health issues.
"It's probably the most substantial issue" facing Internet broadcasters, said Dave Goldberg, vice president and general manager for music at Yahoo, which operates a Web music service.
The most substantial issue in the training process of each 2 p + q − 1 ANNs for change point estimation purpose is collecting proper training data sets.
Not a truly substantial issue, but it bothered me.
Second, data provenance is another substantial issue in predictive toxicology.
