Discovery of high-impact DNMs requires substantial high-resolution interrogation of partial or complete genomes of families via resequencing.
The range of different chemical transformations performed by P450s is also substantial, and continues to expand through interrogation of the properties of novel P450s and by protein engineering studies.
The accounts depict a high-pressure environment at the prison, particularly within the interrogation center, where military intelligence personnel exerted substantial influence over a cellblock where most of the notorious abuses at Abu Ghraib apparently took place.
They had to apply for an exit visa and passport, pay a substantial fee, obtain permission from their employer and undergo an interrogation from the police.
Sure, you'd surface a substantial number of false positives, but it's nothing some light investigation and/or interrogation couldn't suss out.
The result is that I am totally convinced that the authors are correct in their conclusions and the only substantial weakness is that they don't go a little farther in the interrogation of the MICOS complex or the QIL1 protein.
He said it should have "wide-ranging powers" and a "substantial investigative capability" to look into the UK's role in the CIA's interrogation programme.
She wrote that the case represented "a substantial retreat from the protection against compelled self-incrimination that Miranda v. Arizona has long provided during custodial interrogation", and that "[S]uspects must now unambiguously invoke their right to remain silent — which, counterintuitively, requires them to speak.
Although we examined small cohorts, the independent interrogation of discovery and validation sets using comprehensive genomic microarrays (including 482,421 CpGs) and its combined analysis provide substantial strength to our results.
Since then there have been substantial new allegations, including from a senior US official, that British-owned Diego Garcia was used as a "black site" for interrogation as well as transit of detainees, post-9/11.
