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The phrase "substantial information has" is correct and usable in written English.
You can use it when discussing the existence or availability of significant or important information in a particular context. Example: "The research study indicates that substantial information has been gathered regarding the effects of climate change on local ecosystems."
Exact(2)
No substantial information has been provided".
All five attackers, about whom no substantial information has been made public, were soon killed.
Similar(57)
No substantial information had come out.
Since then substantial new information has become available necessitating an update of the guidelines.
It has been estimated that in Europe approximately one million individuals are carriers of an MMR defect. 2 In 2007, a group of European experts (the Mallorca group) published guidelines for the clinical management of LS. 3 Since then substantial new information has become available necessitating an update of the guidelines.
Although a substantial amount of information has been compiled over the past decade about target genes regulated by YY1, much less evidence has been gathered to provide a model for its mode of action and, more importantly, its regulation.
Although the analysis by Shepard and others provided valuable results, a substantial amount of information has emerged since its publication in 2004.
Following the work by Sørlie and colleagues that presented the intrinsic molecular subgroups of BC based on gene expression patterns, a substantial amount of information has elucidated the complexity in pathways driving the different BC subgroups.
The Review by Arredondo-Peter et al. presents our current knowledge on the fascinating field of plant non-symbiotic (nsHb) and truncated hemoglobins (tHb), for which substantial, but scattered, information has accumulated over the past twenty years.
A substantial amount of new information has been recently published concerning miR-146a/b-5p miR-146a/b-5p miR-146a/b-5p
The chapter on adverse effects has been greatly expanded from the second edition because a substantial body of new information has since been gathered.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com