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Despite substantial infiltration of PDPC into raftlike domains, there appears to be minimal effect on the order of SM, implying the existence of internal structure that limits contact between SM and PDPC.
In our DIO models, we observed substantial infiltration of BMDCs into fat tissue (Figure 1D).
A cardinal feature associated with TAO is the substantial infiltration of both B and T lymphocytes within orbital connective tissues [3] [5].
Here, we have demonstrated substantial infiltration of immune cells into the testes, showing both an early immune response during acute SCI, and a sustained presence of immune infiltrate in chronic SCI.
While vehicle-treated eyes showed substantial infiltration of corneal tissue by blood vessels, DARPin treated eyes exhibited both a reduced length and density of infiltrating vessels (Fig. 5).
Congestion, hemorrhage, necrosis and parenchyma consolidation were observed in the lungs, and extensive serous and fibrinous exudates had accumulated together with a substantial infiltration of inflammatory cells.
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The results showed that although both TKO and DKO chimeric animals exhibited substantial lymphocytic infiltration in multiple organs, some tissues from TKO chimeras, such as the small intestine, displayed notably increased infiltration compared with the corresponding tissues from DKO chimeras.
Achieving substantial cellular infiltration within the electrospun matrix in vitro remains time consuming and challenging.
The open weave design, with larger spaces between individual fibers and greater fiber diameters beneficially allowed for substantial cell infiltration throughout the scaffolds.
In the rat spinal cord, bridges implanted into a lateral hemisection supported substantial cell infiltration, aligned cells within the channels, axon growth across the channels, and high levels of transgene expression at the implant site with decreasing levels rostral and caudal.
Similarly, suboptimal inhibition of Pin1 leads to severe rejection pathology with substantial cellular infiltration and hemorrhage (Figure 6).
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