Sentence examples for substantial in which from inspiring English sources

A mainstream writer who often treads dangerously close to standard Richard Curtis feelgood rom-com territory, but always manages to pull back and deliver something rather darker and substantial in which his characters are seldom spared the consequences of their actions.

In simulation studies, we found that the type I error rate of the proposed test was in agreement with the nominal type I error level and that the proposed test had overall moderate power after adjustment for type I error rate, except when the between-trial variance was substantial in which case the empirical type I error rate was considerably inflated and the empirical power was low.

What's more, quoted companies in the US and UK stock exchanges are obliged to reveal all the subsidiaries they either own outright or have substantial stakes in which are considered to be materially important.

But he quickly made it clear that he regarded the exchange as anything but funny, criticizing Mr. Bush and saying Mr. McCain "still hasn't spelled out one substantial way in which he'd be different from George Bush's foreign policy".

The unpredictable side effects of a majority currently used drugs are the substantial issue, in which patients and physicians are forced to deal with.

People who think of game theory as an explanatory and/or normative theory of strategic rationality have generated a substantial literature in which the merits and drawbacks of a large number of refinements are debated.

Following a substantial rebuild, in which the workshops had to construct the missing parts themselves, the locomotive returned to service on 22 December 2012.

This localization is indicative of substantial amplification in which a shallow external gradient is amplified to produce a steep internal gradient of certain proteins.

Even though the mechanisms provide a comparable overall fit to the data, there are substantial differences in which aspects of the data are fitted best (Figure 3).

By contrast, using all expression data simultaneously provides substantial constraints in which non-systematic noise cancels out effectively [73].

This notion also has a more substantial aspect in which the sense of "I-me-myself" persists over time and across different and changing modalities of conscious life.