Sentence examples for substantial in the first from inspiring English sources

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The sales are substantial; in the first six months of 2011, for example, the state's Indian nations imported 9.6 million cartons of brand-name cigarettes, according to the State Department of Taxation and Finance.

In contrast the GEBV accuracy was more persistent, although the drop in accuracy was substantial in the first generation.

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The potential importance of studying such factors for the quality as well as for the economics of health care is substantial in the second most expensive health care system of the world with still rising costs [ 6].

But the Congressional Budget Office says if Congress repealed the formula and allowed payments to doctors to grow by the rate of medical inflation, the costs could be substantial: $65 billion in the first five years and nearly $200 billion in the next five years.

Plenty of cause for optimism there, you might think, except that when United last won the trophy, in 2003, it was with a side containing no players destined to make substantial careers in the first team (the closest candidates were Phil Bardsley, Chris Eagles and Kieran Richardson).

For a constant notch depth, it is found that there is a substantial reduction in the first six frequencies as notch angle decreases.

Mouse Twisted gastrulation gene (Twsg1) expression is found throughout embryonic development, including substantial levels in the first branchial arch that gives rise to the submandibular salivary gland (SMG).

One general observation is the substantial reduction in the first six frequencies as the sector angle increases for all plates, except in the first two modes of plates having free free radial edges.

Reading, themselves on a torrid run of eight losses in 12 games, rarely put the Canaries rear guard under substantial pressure in the first half, but were gifted two goals by inept City defending at set-pieces.

After a substantial decline in the first 36 weeks of the study, the placebo/delayed-treatment cohort demonstrated stabilization in walking ability at week 48, i.e., 12 weeks after initiation of treatment with eteplirsen when meaningful levels of dystrophin were likely produced, with <10 m decline through 120 weeks.

While the center has exceeded expectations for simulation program development and use, and has benefited from some of the decisions of the initial design team, the facility and the programming resources have required substantial changes in the first 3 years of its existence.

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