Sentence examples for substantial in the development from inspiring English sources
Oxidative stress is believed to be substantial in the development of atherosclerosis [ 26].
In recent years, the need of particle-physics collider and neutrino experiments to cover very large detection areas (thousands of square meters) has driven a substantial progress in the development of detectors technologically more advanced, cheaper and simpler to handle.
The whole BioCreative experience highlighted that in order to obtain substantial advances in the development of text-mining methodologies, it is necessary to develop close collaboration among different communities: text miners, database curators and ontology developers.
With the recent focus on the sequencing of complete nuclear genomes has come a substantial interest in the development of high-throughput, low cost sequencing platforms capable of much more substantial sequence outputs than has been possible with conventional sequencers.
"It is clear that the plaintiffs have made substantial investments in the development and protection of their brand-specific ingredient information," Judge O'Toole wrote, "and that there would be a substantial loss of competitive advantage if they were required to disclose that information for publication by the Commonwealth".
Failure to do so could cause substantial delays in the development process.
Moreover, folk medicine has played a substantial role in the development of modern pharmacology.
In the early to mid-2000s, NASA made substantial progress in the development of solar sail propulsion systems.
The last decades have witnessed substantial efforts in the development of several detector technologies for X-ray fluorescence (XRF) applications.
All authors have made substantial contributions in the development of the topic, and have made a synthesis of both approaches to arrive at the exposed conclusions.
Despite impressive advances in combination antiretroviral therapy (cART) to treat HIV, and substantial progress in the development of prevention interventions, a protective vaccine has remained elusive.
