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From our experimental evaluation we conclude that the addition of only one binding-relevant sub-structural feature of a known ligand can substantial improve the enrichment factors in the virtual screening.
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The MA-rich passivation through Pb-N bonding at interface and boundary contributes to the substantial improved stability.
However, together, these findings combined with previous studies on care coordination differences between DHS and KP [ 17], and on quality improvements within the KP system [ 34, 40], suggest substantial opportunities to improve the quality and efficiency of care in Denmark for patients with chronic medical conditions, compared to the KP benchmark.
Although moving inpatient surgeries to outpatient settings has lowered the cost of care, substantial opportunities to improve the value of outpatient surgery remain.
Editors and funders hold substantial power to improve the quality of AR and reduce publication bias.
The key to winning is not necessarily to submit more proposals, but a substantial effort to improve the quality of Italian proposals.
Since many reputable firms are making quite substantial efforts to improve the gender balance I think it can actually work in your favor these days if you're a woman - provided, you have the right skill set.
JC participated in the design of the study, contributed to the interpretation of data and critically reviewed the draft of the manuscript providing substantial contributions to improve the analysis.
There is a substantial need to improve the immunogenicity of MVA-based vaccines, which are currently being developed for use against a number of prominent infectious diseases including AIDS, malaria, and tuberculosis, as well as human cancers.
Two reviews showed that financial-incentive programs have substantial evidence to improve the distribution of human resources for health.
Thus, there may substantial room to improve the quality of care, which is a second path to increasing the efficiency of services.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com