These two strong factors imprint a substantial cultural and conceptual unity upon all these housing types.
After a handful of low-key releases, cuddly Tyneside troubadour Richard Dawson hooks up with Domino's increasingly substantial Weird World imprint for another skewed slice of ramshackle Northumbrian psycho-drama.
We noticed that a substantial number of imprinted genes displaying weak to moderate parental bias localize to the vicinity of imprinted genes showing stronger parental bias.
Based on recent predictions, the number of mammalian imprinted genes may range between 100 and 600 genes [ 1- 4], i.e. a substantial number of imprinted genes are already identified.
Although expression differences between parental alleles are commonly assumed to be all-to-none, a substantial number of imprinted genes have been shown to exhibit a biased expression from one of the parental alleles in at least some tissues (Dao et al., 1998; Lewis et al., 2004; Khatib, 2007; Babak et al., 2008; Menheniott et al., 2008; Tierling et al., 2009; Gregg et al., 2010; Gregg, 2014).
Such definition, however, is incomplete since a substantial number of known imprinted genes appear preferentially expressed from one of the parental alleles.
The potential role of TEs in establishing or maintaining imprinted expression coupled with the evolutionary forces that select for parent-of-origin specific expression suggest that substantial intraspecific variation in imprinting could exist.
Although it is not possible to determine whether ASHM is controlling the imprinting at known imprinted loci, or whether it is simply a consequence, the enrichment of ASHM around known imprinted loci is substantial.
Dr. Dulac said that she expects a substantial, though lesser, proportion to be imprinted in people — maybe some 1 percent of the genome — because humans are more monogamous than mice and so the parents' interests are more closely aligned.
In addition to typical seasonal infections, IAV can also undergo substantial changes (recombination/antigenic shift) that leave imprints of infection with little to no protective immunity and uplift mortality rate even among healthy young adults infected with IAV (Horimoto and Kawaoka, 2001; Palese, 2004).
