Sentence examples for substantial immune response from inspiring English sources
Based on these results, we conclude that SCI is followed by compromised BTB integrity by as early as 72 hours post-injury in rats and is accompanied by a substantial immune response within the testis.
Two doses of aluminum adjuvanted H5N1 split vaccine elicited a substantial immune response even in naïve children aged 6 months to 9 years, although a higher dose of antigen per child (30 µg) was used than what is used in a seasonal inactivated influenza vaccine [11].
Immunogenicity of XTEN has previously been tested in animals, and it was determined that XTEN did not elicit a substantial immune response.
There is strong evidence that raltegravir can achieve significant and sustained suppression of viral RNA levels to less than 50 copies/mL and substantial immune response in drug-resistant HIV-1 patients.
By contrast, we have observed substantial immune responses towards mature amyloid fibrils in the control group and subsiding, but still pronounced, reactivity in early PD and to a lesser extend in late PD as measured by Western blotting (Figure 5A).
The summary of Western blot analysis is presented in the box-plots in Figure 5A for each examined group, demonstrating substantial immune responses towards α-synuclein amyloid fibrils in all of them.
In addition, although, unmethylated CpG motifs within the plasmid DNA vector have also been shown to contribute to the immunogenicity of DNA vaccines [45], [46], cloning additional CpG motifs or adding CpG-ODN to the DNA vaccine rendered substantial immune responses [47], [48].
Several trials have indicated such vectors are safe and can induce substantial immune responses against pathogens such as HCV (Barnes et al., 2012, Colloca et al., 2012).
All antigens were formulated in QS21 adjuvant that had previously demonstrated a substantial dose-sparing ability as well as eliciting a strong immune response [15].
Especially subcutaneous administration of FLU-NA-DIII induced strong immune responses and afforded substantial protection against infection with WNV-NY99 in mice.
This effect may be attributable to the multiple infusion schedule, which may lead to a substantial humoral immune response against the CAR with murine SS1 scFv.
